Comments for Pharma Strategy Blog http://pharmastrategyblog.com Commentary and insights on Pharma & Biotech new product development with a focus on oncology and hematology Wed, 22 Feb 2012 03:24:00 +0000 hourly 1 http://wordpress.org/?v=3.3.1 Comment on Cancer Clinical Trials: Companion Diagnostics or Gene Sequencing? by maverickny http://pharmastrategyblog.com/2012/02/cancer-trials-companion-diagnostics-or-gene-sequencing.html/#comment-1556 maverickny Wed, 22 Feb 2012 03:24:00 +0000 http://pharmastrategyblog.com/?p=4987#comment-1556 Hi Doc!  Good to see you back, hope all is well. Hope to catch you at ASCO this year... Hi Doc!  Good to see you back, hope all is well. Hope to catch you at ASCO this year…

]]> Comment on Cancer Clinical Trials: Companion Diagnostics or Gene Sequencing? by Docnuman http://pharmastrategyblog.com/2012/02/cancer-trials-companion-diagnostics-or-gene-sequencing.html/#comment-1554 Docnuman Tue, 21 Feb 2012 22:35:00 +0000 http://pharmastrategyblog.com/?p=4987#comment-1554 Insightful and useful article Insightful and useful article

]]> Comment on Cancer Clinical Trials: Companion Diagnostics or Gene Sequencing? by maverickny http://pharmastrategyblog.com/2012/02/cancer-trials-companion-diagnostics-or-gene-sequencing.html/#comment-1553 maverickny Tue, 21 Feb 2012 22:18:00 +0000 http://pharmastrategyblog.com/?p=4987#comment-1553 Agreed it will take a long time but the good news is that finally we are making some progress on the complex networks and starting to tease out a few drivers and also the causes of primary and secondary resistance.  You've just reminded me of something else I meant to post on in breast cancer - stay tuned! Agreed it will take a long time but the good news is that finally we are making some progress on the complex networks and starting to tease out a few drivers and also the causes of primary and secondary resistance.  You’ve just reminded me of something else I meant to post on in breast cancer – stay tuned!

]]> Comment on Cancer Clinical Trials: Companion Diagnostics or Gene Sequencing? by maverickny http://pharmastrategyblog.com/2012/02/cancer-trials-companion-diagnostics-or-gene-sequencing.html/#comment-1552 maverickny Tue, 21 Feb 2012 22:15:00 +0000 http://pharmastrategyblog.com/?p=4987#comment-1552 Fixed - good catch! Fixed – good catch!

]]> Comment on Cancer Clinical Trials: Companion Diagnostics or Gene Sequencing? by Jonathan Mandelbaum http://pharmastrategyblog.com/2012/02/cancer-trials-companion-diagnostics-or-gene-sequencing.html/#comment-1551 Jonathan Mandelbaum Tue, 21 Feb 2012 20:47:00 +0000 http://pharmastrategyblog.com/?p=4987#comment-1551 Very exciting times for oncology drug dev! Completely agree that the understanding what the drivers/passengers in every given tumor type will be key to this approach. There are already examples that drivers in one type of cancer may not necessarily behave the same way in other tumor types (eg. in your previous post on de novo resistance to BRAFi in V600E CRC). Unfortunately teasing apart the functional consequences of all these mutations will take MANY years of academic research using in vitro systems, mouse models, etc...The cancer revolution has begun but unfortunately it will not happen overnight. Very exciting times for oncology drug dev! Completely agree that the understanding what the drivers/passengers in every given tumor type will be key to this approach. There are already examples that drivers in one type of cancer may not necessarily behave the same way in other tumor types (eg. in your previous post on de novo resistance to BRAFi in V600E CRC). Unfortunately teasing apart the functional consequences of all these mutations will take MANY years of academic research using in vitro systems, mouse models, etc…The cancer revolution has begun but unfortunately it will not happen overnight.

]]> Comment on Cancer Clinical Trials: Companion Diagnostics or Gene Sequencing? by Svkmp http://pharmastrategyblog.com/2012/02/cancer-trials-companion-diagnostics-or-gene-sequencing.html/#comment-1550 Svkmp Tue, 21 Feb 2012 19:19:00 +0000 http://pharmastrategyblog.com/?p=4987#comment-1550 Nice article. The 'r' in Dr. Kurzrock's name is missing in the answers. Nice article. The ‘r’ in Dr. Kurzrock’s name is missing in the answers.

]]> Comment on My take on the crizotinib Xalkori FDA approval by Xy2008080808 http://pharmastrategyblog.com/2011/08/my-take-on-the-crizotinibxalkori-fda-approval.html/#comment-1546 Xy2008080808 Sat, 18 Feb 2012 10:02:00 +0000 http://pharmastrategyblog.com/?p=4069#comment-1546 hi,everyone I am from China, and here we don't have this medicine. But one of my friends with lung cancer need this medicine, actually she is so young (40 years old). Could you tell me whether this medicine can prescirbed by the family doctor or not? If she can have the therapy by this medicine, she would like to go to USA for it. Thank you so much! Yun hi,everyone

I am from China, and here we don’t have this medicine.
But one of my friends with lung cancer need this medicine, actually she is so young (40 years old).

Could you tell me whether this medicine can prescirbed by the family doctor or not?
If she can have the therapy by this medicine, she would like to go to USA for it.

Thank you so much!

Yun

]]> Comment on Zelboraf approved by the FDA in BRAF V600E metastatic melanoma by Drishaqkhan http://pharmastrategyblog.com/2011/08/zelboraf-approved-by-the-fda-in-braf-v600e-metastatic-melanoma.html/#comment-1545 Drishaqkhan Tue, 14 Feb 2012 18:17:00 +0000 http://pharmastrategyblog.com/?p=4027#comment-1545 Hi Sir/Madam I would request to know,where from to get Zelboraf for my brother as free sample,clinical trials or at least on cheep price.His lymph nodes tissue blocks came out be sensitive to the test BRAF V600.Please help him on humanitarian grounds. Best Regards Asad  Hi Sir/Madam
I would request to know,where from to get Zelboraf for my brother as free sample,clinical trials or at least on cheep price.His lymph nodes tissue blocks came out be sensitive to the test BRAF V600.Please help him on humanitarian grounds.
Best Regards
Asad 

]]> Comment on The role of the Androgen Receptor in breast cancer by pharma exhibition http://pharmastrategyblog.com/2012/02/the-role-of-the-androgen-receptor-in-breast-cancer.html/#comment-1544 pharma exhibition Tue, 14 Feb 2012 16:21:00 +0000 http://pharmastrategyblog.com/?p=4948#comment-1544 Really the great post, which have worth.. I appreciate this post. Really the great post, which have worth.. I appreciate this post.

]]> Comment on Fluid-based early detection biomarkers in cancer by Mesothelioma Symptoms http://pharmastrategyblog.com/2010/07/fluidbased-early-detection-biomarkers-in-cancer.html/#comment-1543 Mesothelioma Symptoms Tue, 14 Feb 2012 07:43:00 +0000 http://pharmastrategyblog.com/2010/07/fluidbased-early-detection-biomarkers-in-cancer.html/#comment-1543 My friend's dad was recently diagnosed with non-small cell lung cancer but it is good that he is diagnosed in the initial stage of it. My friend’s dad was recently diagnosed with non-small cell lung cancer but it is good that he is diagnosed in the initial stage of it.

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